Kantar Health Blog

  • Jay Grisolano
    ASCO Annual Meeting 2017 - Approximately a quarter of breast cancer patients are classified as HER2-positive, according to Kantar Health’s 2016 Treatment Architecture data. Effective targeted agents for the HER2 receptor, such as Herceptin (trastuzumab; Roche) and Perjeta (pertuzumab; Roche), have been developed for this particular patient segment and have greatly improved clinical outcomes for these patients. APHINITY did meet its primary endpoint showing that addition of Perjeta to Herceptin and chemotherapy as adjuvant treatment achieved a statistically significant improvement in IDFS. These data suggest that the triplet may become an option for adjuvant treatment of HER2+ early breast cancer.
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  • Jay Grisolano
    ASCO Annual Meeting 2017 - Data were presented on LATITUDE, a randomized Phase III trial comparing Zytiga/prednisone plus androgen deprivation therapy (ADT) versus placebos plus ADT in newly-diagnosed high-risk metastatic hormone-naive prostate cancer (mHSPC). Based on these data, Zytiga will likely become the new standard of care for high-risk mHSPC patients. As the discussant, Eric Small, MD, stated, “LATITUDE was a profoundly positive study.”
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  • Opdivo Shows Appetite for Gastric Cancer

    by Jay Grisolano | Jan 20, 2017
    Jay Grisolano
    Oncology Conference Insight: ASCO GI 2017 --- Before Cyramza® (ramucirumab, Eli Lilly and Co) was approved by the FDA in 2014, there were no targeted therapy regimens approved for use in relapsed/refractory gastric cancer. Cyramza’s approval as a monotherapy or in combination with paclitaxel after prior fluoropyrimidine- or platinum-containing systemic therapy was based on the positive results of two Phase III studies in relapsed gastric patients.
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  • Jay Grisolano
    Oncology Conference Insight: ASH 2016 --- Immunotherapies such as checkpoint inhibitors have had a dramatic impact on treatment paradigms for many tumor types over the past few years, and their full potential is far from being realized. Hot on the heels of checkpoint inhibitors are engineered, adoptive T-cell therapies that represent another promising advancement.
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  • GALLIUM turns Gazyva into gold in NHL

    by Jay Grisolano | Dec 5, 2016
    Jay Grisolano
    Oncology Conference Insight: ASH 2016 --- In the management of non-Hodgkin lymphoma (NHL), Rituxan-based therapy forms the foundation for therapy in all settings. This holds true for most subtypes of NHL, including follicular lymphoma, mantle cell lymphoma, and diffuse B-cell lymphoma. While Rituxan-based therapy is highly effective and leads to improvement in survival rates, patients are rarely cured, and relapse is common, occurring in about 20-30% of patients.
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